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在医学进步领域,阿尔茨海默病研究有了突破性发现,新获批的药物 lecanemab 在减缓病情进展方面展现出显著希望。一项发表在《新英格兰医学杂志》的研究表明,每两周静脉注射 lecanemab 对认知衰退和脑萎缩有重大影响。在涉及 1700 多名早期阿尔茨海默病患者的临床试验中,其认知衰退率相比安慰剂降低了 27%,脑萎缩减少了 16%。这一发现引起医学界轰动,被专家称为重大突破。美国食品药品监督管理局(FDA)的批准标志着阿尔茨海默病治疗的转折点,为早期患者提供了急需的治疗选择,虽不能治愈但能延长严重认知障碍和功能丧失前的时间。医学界在继续探索其全部潜力,对抗阿尔茨海默病的斗争带着新的活力继续。


英语学习要点



  • 词汇:ever-evolving(不断发展的)、groundbreaking(开创性的)、debilitating(使衰弱的)、respite(缓解)、atrophy(萎缩)、hail(称赞)、paradigm shift(范式转变)、unwavering(坚定不移的)、devastating(毁灭性的)等。

  • 短语:delve into(深入研究)、a glimmer of hope(一线希望)、slow the progression of(减缓……的进展)、compared to(与……相比)、mark a turning point(标志着转折点)、navigate the challenges(应对挑战)等。


原文:

As we delve into the ever-evolving realm of medical advancements, a groundbreaking discovery in Alzheimer's research has emerged, offering a glimmer of hope in the fight against this debilitating disease. A newly approved drug, lecanemab, has shown remarkable promise in slowing the progression of Alzheimer's, potentially offering respite and hope to countless individuals and families affected by this cruel condition.


According to a groundbreaking study published in The New England Journal of Medicine, lecanemab, administered intravenously every two weeks, has demonstrated a significant impact on cognitive decline and brain atrophy. In clinical trials involving over 1,700 patients with early Alzheimer's, lecanemab was found to reduce the rate of cognitive decline by an impressive 27%, compared to a placebo. Additionally, the drug was shown to reduce brain atrophy, a hallmark of Alzheimer's disease, by 16%.


The findings have sent shockwaves through the medical community, with experts hailing this discovery as a major breakthrough in the quest to combat Alzheimer's. Dr. Thomas Wisniewski, a neurologist at New York University Langone Health, called the results a paradigm shift, adding that "this is the first time we've seen a drug that can actually slow down the disease process."


The approval of lecanemab by the U.S. Food and Drug Administration (FDA) marks a turning point in Alzheimer's care, providing a much-needed therapeutic option for patients in the early stages of the disease. While lecanemab does not cure Alzheimer's, it offers the potential to extend the time before patients experience severe cognitive impairment and loss of function. 


For families and caregivers, this newfound hope can provide a lifeline of support as they navigate the challenges of this complex disease.


As the medical community continues to explore the full potential of lecanemab and other promising treatments, the battle against Alzheimer's rages on with renewed vigor. This groundbreaking discovery serves as a testament to the unwavering determination of scientists, researchers, and clinicians who remain committed to finding solutions for this devastating condition.

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我看到啦!!!感谢主播!!!
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