参考文献(找不到我的微信滴:A2016A05A)
1. Campisi, J., Kapahi, P., Lithgow, G. J., Melov, S., Newman, J. C., & Verdin, E. (2019).
From discoveries in ageing research to therapeutics for healthy ageing.
*Nature, 571*(7764), 183-192.
2. Justice, J. N., Nambiar, A. M., Tchkonia, T., et al. (2019).
Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study.
*EBioMedicine, 40*, 554-563.
3. López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013).
The hallmarks of aging.
*Cell, 153*(6), 1194-1217.
4. Sinclair, D. A., & LaPlante, M. D. (2019).
*Lifespan: Why We Age—and Why We Don’t Have To.*
Atria Books.
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The Achilles’ heel of senescent cells: From transcriptome to senolytic drugs.
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说明:
- Campisi 2019 :系统总结了衰老生物学与治疗策略。
- Justice 2019 :达沙替尼+槲皮素(D+Q)的首个人体临床试验。
- López-Otín 2013 :经典衰老标志理论框架。
- Sinclair 2019 :书籍,涵盖NAD+/Sirtuins与抗衰老机制。
- Zhu 2015 :首次提出Senolytics概念及D+Q联用策略。
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