在本期节目中，我们深入探讨了线粒体这一细胞中的“能量工厂”及其在抗衰老和健康中的关键作用。从线粒体的基本结构和功能，到它与氧化应激、衰老及相关疾病的关系，再到如何通过饮食、运动、作息和补充剂来优化线粒体健康，本期内容涵盖了这一新兴科研领域的核心话题。无论你是健康爱好者，还是对抗衰老感兴趣的听众，这期节目都将为你提供宝贵的科学见解和实用建议。

时间戳：

00:00:34 - INTRO导言

00:02:30 - AD推广——旭福褪黑素

00:04:30 - 什么是线粒体？线粒体的基本结构

00:07:35 - 线粒体的主要功能：为什么它是细胞的“能量工厂”？还有哪些重要功能？

00:10:25 - 线粒体与氧化应激：活性氧物质（ROS）的产生以及肌体的衰老

00:16:10 - 抗氧化机制：内源性抗氧化剂&外源性抗氧化剂

00:21:51 - 抗衰老饮食策略：避免高糖高脂饮食、补充omega3、充足的蛋白质摄入、地中海饮食法、生酮饮食法、其他膳食补充剂

00:29:32 - 卡路里限制/热量摄入限制/间歇性断食/禁食促进线粒体健康并减少氧化应激

00:33:14 - 运动锻炼

00:35:00 - 睡眠

00:36:26 - OUTRO结语

BGM: Touch by THE DRIVER ERA, Ross Lynch, Rocky

赞助商信息：感谢本期节目的赞助商旭福褪黑素！

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拍2共188.00，折单件94

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参考文献与延伸阅读：

1.    Anu Suomalainen, Jodi Nunnari. 2024. Mitochondria at the crossroads of health and disease.

2.    Aleksandra Kaliszewska, Joseph Allison, Matteo Martini, Natalia Arias. The Interaction of Diet and Mitochondrial Dysfunction in Aging and Cognition.2021

3.    Evripides Lakovou, Malamati Kourti. A Comprehensive Overview of the Complex Role of Oxidative Stress in Aging, The Contributing Environmental Stressors and Emerging Antioxidant Therapeutic Interventions. 2022.

4.    Martha Guevara-Cruz, et al. 2024. Intermittent fasting, calorie restriction, and a ketogenic diet improve mitochondrial function by reducing lipopolysaccharide signaling in monocytes during obesity: A randomized clinical trial.

5.    Jianying Yang, Juyue Luo, Xutong Tian, et al. 2024. Progress in Understanding Oxidative Stress, Aging, and Aging-Related Diseases.

6.    Takeshi Katayoshi, Sachi Uehata, et al. 2023. Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial

7.    Shalender Bhasin, Douglas Seals, et al. 2023. Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns

8.    RV Sekhar, SG Patel, et al. 2011. Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation

9.    Ioannis D Kyriazis, Eleni Vssi, et al. 2022. The impact of diet upon mitochondrial physiology (review)

10. Martha Guevara-Cruz, et al. 2024. Intermittent fasting, calorie restriction, and a ketogenic diet improve mitochondrial function by reducing lipopolysaccharide signaling in monocytes during obesity: A randomized clinical trial

11. Vincent J. Miller, et al. 2020. A ketogenic diet combined with exercise alters mitochondrial function in human skeletal muscle while improving metabolic health